Eurycoma longifolia is a medicinal plant found in South East Asia. It is commonly called Tongkat Ali or Malaysian ginseng, and is traditionally used as a general health tonic, adaptogen, and “anti-aging” remedy to help older individuals adapt to the reduced energy, mood, and libido that often comes with age. Decoctions of Tongkat Ali roots have been used for centuries as an aphrodisiac for loss of sexual desire and function, as well as to treat a range of ailments including post-partum depression, malaria, high blood pressure, and fatigue.
In modern dietary supplements, Tongkat Ali can be found in a variety of products intended to improve libido and sexual function, restore hormonal balance (cortisol/testosterone levels), enhance sports performance, weight loss, improve physical and mental energy, and overall quality of life.
Eurycoma longifolia contains eurypeptides, a 30-39 long amino acid chain, 4300 dalton molecular weight, that are known to have effects in improving energy status and sex drive in studies of rodents. Eurypeptides has been suggested as influencing the release of “free” testosterone from its binding hormone, sex hormone binding-globulin (SHBG).
LJ100® is the only science based Eurycoma Longifolia extract, standardized to 40% Glyco Saponins, 28% Eurypeptides, 30% Polysacharides, and Eurycomanone. Eurypeptides is clinically proven at MIT for its androgenic properties. Created by the original researchers at MIT and University Malaya, this product has shown in human clinical trials - an ability to increase energy, enhance sport performance, promote anabolic state, and increase fat free mass. LJ100® is made from wild crafted Tongkat Ali root from the rainforest of Malaysia. It is produced using a patented extraction technology, with high temperature, high pressure, reverse osmosis water extraction method, ultra filtration process, and freeze dried technology without any filler. LJ100® is protected by a worldwide patent for treatment of sexual dysfunction and male fertility.
(WO 02/17946 A1, US 7,132,117)
First International Journal of Andrology 2011
76 patients with late-onset hypogonadism (LOH) were given 200mg of LJ100® for 1 month. Results show that treatment with LJ100® significantly (P < 0.0001) improved the Aging Male Symptom score and serum testosterone concentration Prior to LJ100® treatment only 35.5% had normal testosterone levels, after the completed treatment 90.8% of the patients showed normal values. Mean serum testosterone also rose from 5.66nm to 8.31nm (46.8% increase). LJ100® is useful as a supplement for LOH and management of hypogonadism.
In a randomized, double-blind, placebo controlled study, 26 men with mild erectile dysfunction were given either 200mg/day of LJ100® or placebo for 12 weeks. The LJ100® group demonstrated statistically significant (p<0.05) higher scores than placebo group at 12 weeks for: Erection Hardness Scale Score, Aging Males Symptom Score, and the Sexual Health Inventory Score, and Sexual Intercourse Assessment. There is a reduction trend of Fat Mass Loss in the LJ100® group in overweight subjects (>25kg BMI) in waist and hips compared to placebo. LJ100® significantly improves sexual performance and satisfaction and was well tolerated with excellent safety profiles (identical to placebo) at 200 mg/day dose for 12 weeks.
Evidence-Based Complementary and Alternative Medicine, Volume 201211
A randomized, double-blind, placebo controlled parallel group study with 109 healthy men were given either 300 mg of LJ100® or placebo for 12 weeks. The LJ100® group showed significantly improvement in the domain Physical Functioning of SF-36, overall Erectile Function domain in IIEF, and sexual libido (14% by week 12). SHBG analysis is lower in LJ100® group compared to placebo (26.8 vs. 30.6). Sperm motility increase 44% (from 33.8% to 48.8%), and semen volume increase 18.2% (from 2.54ml to 3.00ml) in LJ100® group. There is a reduction trend of Fat Mass Loss in the LJ100® group in overweight subjects (>25kg BMI) in the trunk area in the LJ100® group. All safety parameters were comparable to placebo.
Journal of International Society of Sport Medicine 3 (1): S32 20060
Thirty Male subjects were recruited from a 24-hour mountain biking event; 15 were given 100mg of LJ100®, and 15 were given placebo. Saliva samples were collected before and after each lap. Subjects completed 4 laps and provided 8 saliva samples over a 24h period for measurement of cortisol and testosterone by enzyme immunoassay.
Cortisol levels were 32.3% lower in the LJ100® group compared to Placebo (0.552+0.665 versus 0.816+0.775 ug/dl, P < 0.05). Testosterone levels were 16.4% higher in the LJ100® group compared to Placebo (86.72+40.90 versus 72.47+33.77 g/ml, P < 0.05).
Asian Journal of Andrology (2010) 12: 376–380211
75 patients were given 200 mg of LJ100® daily for 9 months. Follow-up semen analyses in these patients showed significant improvement in sperm quality, sperm volume, sperm concentration (65.5% increase), sperm motility, and percentage of sperm with normal morphology (94.9% increase) in men with idiopathic infertility. Spontaneous pregnancies were achieved in 14.7% of couples in our study and the use of a less invasive, cheaper variety of ART became possible in another 60%.
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A method for causing a permanent increase in the length and girth of a male subject's penis, the method comprising treatment comprising the step of (a) administering to the male an effective amount of a vasodilator selected from the group consisting of a vasodilator per se and compositions thereof comprising a pharmaceutically-acceptable diluent or carrier, to induce a cumulative prolonged engorgement of the subject's penis; and (b) repeating step (a) as necessary to cause the increase during the treatment. A potentiator which enhances the effect of the vasodilator may also be used.
1. Consistent vasodilation through administration of vasodilators (L-Arginine) can cause an increase during the treatment.
2. “Potentiators” that increase libido enhances the effect of the vasodilation process will increase the effectiveness of using vasodilators in increasing the length and girth of the penis.
Use of proanthocyanidins as an active ingredient of a stimulator as a source of arginine and a source of nitric oxide in the treatment of erectile dysfunction. The active ingredient stimulates the endothelial NO-synthase enzyme, which acts as a catalyst for the synthesis of nitric oxide from its substrate L-arginine or its salts. The nitric oxide in turn activates theguanylyl cyclase, which leads to an increased development of cyclic guanosine monophosphate, which causes relaxation of smooth muscles.
Blood vessel diameter may increase. The stimulator may also have Sildenafil or enzymes that inhibit an enzyme phosphodiesterase type5 from reducing an amount of the cyclic guanosine monophosphate. The substrate may be amino acid L-arginine, arginine salts or a dipeptide of arginine and aspartic acid.
1. L-Arginine as a source of nitric oxide in the treatment of erectile dysfunction.
2. The combination of L-Arginine and PDE-5 inhibitors (Epimedium, Tongkat Ali, Muira Puama) exponentially increases the effectiveness of L-Arginine to treat erectile dysfunction.
Supplementation of Arginine twice daily for 6 weeks appears to promote blood flow and reduce symptoms associated with increased biomarkers of nitric oxide metabolite (nitrate and urinary cGMP).
Functional testing noted that Arginine outperformed PGE1 (Prostaglandin E1), an erectile dysfunction treatment.
Link to study: http://www.ncbi.nlm.nih.gov/pubmed/9809945
Eurycoma longifolia Jack (Tongkat Ali) were studied using various tests of potency. The results showed that Tongkat Ali produced a dose-dependent, recurrent, and significant increase in the episodes of penile reflexes as evidenced by increases in erection quality of the subjects. These results further provide evidence that Tongkat Ali increases the aphrodisiac potency in treated subjects.
Link to study: http://www.ncbi.nlm.nih.gov/pubmed/9809945
The ingredients that make the SizeVitrexx formula have been carefully chosen for their powerfully intense capabilities. The prominent scientists behind the scenes spent an immense amount of time analyzing and evaluating every single ingredient individually. Once that was documented, they spent a great deal more effort on investigating their combined actions. This was to ensure that we could offer the public the most effective concentration for potent penis enhancement.
Every single ingredient in the SizeVitrexx formula has awesome penis powering properties by themselves. As a concentrated capsule the combination packs a wallop because they boost each other in addition to providing their own actions. We researched suppliers in order to find premium quality herbs from distributors who understand the importance of proper cultivation, harvesting, and storage. We source these plants from their respective indigenous environments for maximum potency.
Malaysian ginseng, also known as Tongkat Ali, is a flowering shrub which is indigenous to the southeastern portion of the Asian continent. Referred to as a bitter medicine it has a rich history within Ancient Chinese Medicine and Philosophy. It has been used as an aphrodisiac, to reduce fever, and an antimicrobial agent among many others. Tongkat Ali was once steeped in hot water for tea or added to coffee. Today it may be found in numerous products such as energy drinks and/or purchased in several forms such as loose, in an extract, or supplemental capsules.
In addition to the many health benefits Tongkat Ali has been proven to effectively elevate testosterone levels. It is often marketed as a booster for overall well-being. This sparked a study conducted by the Biotropics Malaysia Berhad. Two of the most common causes or erectile dysfunction are impaired testosterone levels and stress. This investigation was to determine what the effects, if any, were of Tongkat Ali supplementation. This revealed that it significantly increased testosterone and measurably decreased cortisol exposure.
Avena Sativa is often referred to as wild oats or oat straw. It has been crowned as Natural Viagra and is native to northern portions of Europe. The only temperate setting it cannot survive in is shaded areas. Oat straw grows extremely well in meadows, wastelands, and prepared beds. Earth’s inhabitants has known the medicinal value of this plant for a very long time. Archaeologists found it within Ancient Egyptian Tombs. Many cultures thought Oat Straw promoted proper blood circulation and was often used to treat premature ejaculation as well as impotence.
Oat Straw contains a myriad combination of polyphenols and avenanthramides. These components are said to protect against cardiovascular disorders; prevent and/or inhibit cancer growth; and balance metabolism and hormones to prevent diabetes. The Department of Biochemistry of the University of Allahabad provided scientific validation for these actions as well as Oat Straw’s potential for combating cognitive declination. There is a high correlation between hypertension and erectile dysfunction. There are also many precautions about hypertensive medications and interactions. Oat Straw not only balances hormones and boosts testosterone levels, the Department of Pharmaceutical Sciences discovered that it reduces diastolic and systolic blood pressure considerably.
Ptychopetalum is also called Muira Puama and has earned the nicknames Potency Wood and Viagra of the Amazon. This shrub is indigenous, as would be expected, to the Amazon Rain Forest. Ancient Brazilian cultures have utilized all parts of this plants for medicinal purposes; however, the roots and bark contain the highest concentrations of penis powering properties.
In many cases, men diagnosed with erectile dysfunction are told that it is simply a part of the aging process. The Department of Internal Medicine at the Charles R. Drew University of Medicine & Science completed a trial to determine the effects of Muira Puama as a treatment for ED. It was one of four components in a formula administered to test subjects orally and the results were very similar to PDE5 inhibitor therapy. Muira Puama was found to be effectual in reversing as well as deferring erectile dysfunction related to the aging process.
Panax Quinquefolius is more widely recognized as American Wild Ginseng is a native ivy species found in eastern North American regions. The properties, scientifically referred to as ginsenosides, of American Ginseng are extremely similar to those within Panax ginseng, or Chinese Ginseng. It has been recommended as a panacea for thousands of years as ancient cultures believed that is encourage the free flow of Qi and dramatically enhanced sexual performance.
The University of Hong Kong published clinical study findings for the medicinal potential of Ginseng on NCBI. It was proven effective in four areas of reproduction. It enhanced erectile abilities and improved sperm quality as well as count. This trial also discovered that Ginseng incites the production of testosterone and encourages spermatogenesis as well as shield against chemical insult of the testis.
L-Arginine, an important physiological building block and amino acid group often shortened to Arginine, is primarily responsible for protein biosynthesis. It is commonly prescribed for infants born prematurely and is usually naturally created within the human body. L-Arginine offers several health beneficial mechanisms and can be administered through the consumption of certain plants or animals as well as taken as a supplemental regimen.
A group from the Seminological Laboratory revealed that L-arginine dramatically enhanced the sexual function of test subjects. The report states that over 90% of men had achieved normal erections after completing a three month long daily administered regimen. It went on to say that this was without any adverse side effects.
Andean cultures have been eating Maca Root as a vegetable and using as a medicinal herb for many centuries. These peoples believe that it is a powerful aphrodisiac and acts as a hormone regulator. It offers important nutrients such as essential omega-3 fatty acids, iodine, and zinc. Maca Root has been consumed to combat depression, increase bone density, and promote fertility.
The results of several randomized trials have been published through PMC. One which was published by the Depression Clinical and Research Program said that Maca Root demonstrated promising potential for treating antidepressant related sexual dysfunction. Subjects also presented with increased libido function. The root extract has been proven to counteract the effects of patients experiencing mild instances of erectile dysfunction.
SizeVitrexx is a potent answer to all levels of sexual dysfunction. These powerful properties in this amazing formula will kick start the libido and shift desire into second gear. It will assist consumers in achieving rock hard erections and keep them going the distance for the long marathon. The SizeVitrexx formula has been studied and clinically tested to ensure it provides maximum results.